Welcome To Website IAS

Hot news
Achievement

Independence Award

- First Rank - Second Rank - Third Rank

Labour Award

- First Rank - Second Rank -Third Rank

National Award

 - Study on food stuff for animal(2005)

 - Study on rice breeding for export and domestic consumption(2005)

VIFOTEC Award

- Hybrid Maize by Single Cross V2002 (2003)

- Tomato Grafting to Manage Ralstonia Disease(2005)

- Cassava variety KM140(2010)

Centres
Website links
Vietnamese calendar
Library
Visitors summary
 Curently online :  2
 Total visitors :  6145159

CRISPR Helped to Successfully Prevent and Treat COVID-19 Infections
Sunday, 2022/08/07 | 06:52:16

Researchers led by a team at Duke Health in Duke University used CRISPR technology to successfully prevent and treat COVID infections in proof-of-concept experiments conducted in mice.

 

The experiments modified a currently available lipid nanoparticle to deliver a specific CRISPR-Cas13 mRNA that generates an inhospitable environment in the lungs for SARS-CoV-2 infection. Duke University professor Qianben Wang and colleagues focused on an enzyme that breaks down protein, a protease called cathepsin L, or CTSL, which is abundant in the lungs and has long been identified as playing a key role in SARS-CoV-2 and many other coronavirus infections, enabling the virus to enter host cells and proliferate.

 

Other researchers have attempted to use CTSL inhibitors to thwart coronavirus infections for many years. Lab experiments were promising, but animal tests had disappointing results. Using CRISPR technology, Wang's team was able to create a way to safely initiate CTSL inhibition. CRISPR-Cas13, delivered intravenously through a lipid nanoparticle, diminished CTSL in the lungs of mice, which effectively and safely blocked the SARS-CoV-2 virus from entering cells and infecting the host.

 

For more details, read the article in Duke Health News and Media.

Back      Print      View: 44

[ Other News ]___________________________________________________
  • Beyond genes: Protein atlas scores nitrogen fixing duet
  • 2016 Borlaug CAST Communication Award Goes to Dr. Kevin Folta
  • FAO and NEPAD team up to boost rural youth employment in Benin, Cameroon, Malawi and Niger
  • Timely seed distributions in Ethiopia boost crop yields, strengthen communities’ resilience
  • Parliaments must work together in the final stretch against hunger
  • Empowering women farmers in the polder communities of Bangladesh
  • Depression: let’s talk
  • As APEC Concludes, CIP’s Food Security and Climate Smart Agriculture on Full Display
  • CIAT directly engages with the European Cocoa Industry
  • Breeding tool plays a key role in program planning
  • FAO: Transform Agriculture to Address Global Challenges
  • Uganda Holds Banana Research Training for African Scientists and Biotechnology Regulators
  • US Congress Ratifies Historic Global Food Security Treaty
  • Fruit Fly`s Genetic Code Revealed
  • Seminar at EU Parliament Tackles GM Crops Concerns
  • JICA and IRRI ignites a “seed revolution” for African and Asian farmers
  • OsABCG26 Vital in Anther Cuticle and Pollen Exine Formation in Rice
  • Akira Tanaka, IRRI’s first physiologist, passes away
  • WHO calls for immediate safe evacuation of the sick and wounded from conflict areas
  • Farmer Field School in Tonga continues to break new ground in the Pacific for training young farmers

 

Designed & Powered by WEBSO CO.,LTD