Welcome To Website IAS

Hot news
Achievement

Independence Award

- First Rank - Second Rank - Third Rank

Labour Award

- First Rank - Second Rank -Third Rank

National Award

 - Study on food stuff for animal(2005)

 - Study on rice breeding for export and domestic consumption(2005)

VIFOTEC Award

- Hybrid Maize by Single Cross V2002 (2003)

- Tomato Grafting to Manage Ralstonia Disease(2005)

- Cassava variety KM140(2010)

Centres
Website links
Vietnamese calendar
Library
Visitors summary
 Curently online :  3
 Total visitors :  4282095

Researchers Move Closer to Developing Nitrogen-Fixing Cereal Crops
Saturday, 2020/01/18 | 06:14:44

ISAAA News - January 15, 2020

 

A research group at Massachusetts Institute of Technology (MIT) led by Christopher Voigt, the Daniel I.C. Wang Professor of Advanced Biotechnology, has moved closer to developing nitrogen-fixing cereal crops.

 

To develop nitrogen-fixing cereal grains, the researchers in the Voigt Lab targetted specific genes in the nitrogen-fixing bacteria that operate symbiotically with legumes, called the nif genes. These genes cause the expression of the protein structures (nitrogenase clusters) that fix nitrogen from the air. However, this genetic engineering work is a major technical challenge as the nif pathway is very large and involves many different genes. Transferring a large gene cluster is a difficult task and not only requires the researchers themselves to transfer the genes, but also replicate the cellular components responsible for controlling the pathway.

 

This leads the researchers into another challenge. The microbes responsible for nitrogen fixation in legumes are bacteria (prokaryotes) while gene expression is completely different in plants, which are eukaryotes. Reengineering the nif pathway in a eukaryote is tantamount to a complete system overhaul. The Voigt lab found a workaround and targetted organelles within the cell — specifically, the chloroplasts and the mitochondria. The team then designed a nitrogenase gene delivery system using yeast. They inserted the nitrogenase genes into the yeast nuclei, which are then targeted to mitochondria using peptide fusions and resulted in the first eukaryotic organism to demonstrate the formation of nitrogenase structural proteins.

 

This research obtained groundbreaking results, moving closer to fertilizer independence through nitrogen-fixing cereals. The research team made headway in targeting nitrogenase to mitochondria and were able to express a complete NifDK tetramer — a key protein in the nitrogenase cluster — in yeast mitochondria. Despite these milestones, more work is yet to be done.

 

For more details, read the article on MIT News.

 

Figure: The Voigt Lab at MIT is first testing its novel plant engineering techniques on tobacco plants in the lab. The goal is to imbue these plants with nitrogen-fixing capabilities through genetic editing. Photo Source: Lisa Miller/J-WAFS.

Back      Print      View: 20

[ Other News ]___________________________________________________
  • Beyond genes: Protein atlas scores nitrogen fixing duet
  • 2016 Borlaug CAST Communication Award Goes to Dr. Kevin Folta
  • FAO and NEPAD team up to boost rural youth employment in Benin, Cameroon, Malawi and Niger
  • Timely seed distributions in Ethiopia boost crop yields, strengthen communities’ resilience
  • Parliaments must work together in the final stretch against hunger
  • Empowering women farmers in the polder communities of Bangladesh
  • Depression: let’s talk
  • As APEC Concludes, CIP’s Food Security and Climate Smart Agriculture on Full Display
  • CIAT directly engages with the European Cocoa Industry
  • Breeding tool plays a key role in program planning
  • FAO: Transform Agriculture to Address Global Challenges
  • Uganda Holds Banana Research Training for African Scientists and Biotechnology Regulators
  • US Congress Ratifies Historic Global Food Security Treaty
  • Fruit Fly`s Genetic Code Revealed
  • Seminar at EU Parliament Tackles GM Crops Concerns
  • JICA and IRRI ignites a “seed revolution” for African and Asian farmers
  • OsABCG26 Vital in Anther Cuticle and Pollen Exine Formation in Rice
  • Akira Tanaka, IRRI’s first physiologist, passes away
  • WHO calls for immediate safe evacuation of the sick and wounded from conflict areas
  • Farmer Field School in Tonga continues to break new ground in the Pacific for training young farmers
Designed & Powered by WEBSO CO.,LTD