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EFSA GMO Panel Finds No Safety Concerns with the Food Enzyme Carboxypeptidase C from GM Aspergillus Niger
Wednesday, 2024/11/06 | 08:16:08

The European Food Safety Authority (EFSA) GMO Panel evaluated the safety of the food enzyme carboxypeptidase C produced from the genetically modified (GM) Aspergillus niger strain PEG by DSM Food Specialties B. V.

 

The genotoxicity and systemic toxicity tests showed no safety concerns and adverse effects level of 1850 mg TOS/kg bw per day, the highest dose tested, compared to the estimated dietary exposure. The homology search also identified a match between the food enzyme's amino acid sequence and a wheat allergen. Although risks cannot be excluded, the Panel suggests that the risk for allergic reactions to dietary exposure remains low.

 

The evaluation showed that the food enzyme is free from viable cells of the production organism and its DNA. The Panel concludes that the food enzyme and the genetic modifications conducted do not give any safety concerns under the intended conditions of use.

 

For more information, read the safety evaluation from EFSA.

See https://www.isaaa.org/kc/cropbiotechupdate/article/default.asp?ID=21060

 

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