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Researchers Reveal Novel Genetic Basis of Pest Resistance to Biotech Crops
Sunday, 2024/11/10 | 06:22:58

Figure: The corn earworm, also known as cotton bollworm or Helicoverpa zea, has shown an ability to quickly evolve resistance in the field to genetically engineered crops. University of Arizona researchers in the College of Agriculture, Life and Environmental Sciences are studying a unique genetic factor that helps one of the U.S.’s major crop pests resist transgenic crops. Photo Source: University of Arizona.

 

Researchers from the University of Arizona Department of Entomology in the College of Agriculture, Life and Environmental Sciences used genomics to investigate the genetic changes causing resistance to transgenic crops in field populations of the corn earworm, also known as cotton bollworm or Helicoverpa zea.

 

The researchers, led by Bruce Tabashnik, head of the Department of Entomology, discovered that in this pest, field-evolved resistance was not associated with any of the 20 genes that have been previously implicated in resistance to the pest-killing proteins in transgenic crops. The U of A researchers worked with colleagues from Texas A&M University who used bioassays to evaluate resistance by testing the insects from the field. The collaborating research teams analyzed 937 corn earworms from 17 sites in seven states across the southern United States, sampled from 2002 to 2020.

 

"We carefully examined 20 genes that affected how pests responded to Bt proteins in previous studies. Our evidence indicates changes in these genes are not causing resistance to Bt crops in wild populations of the corn earworm," said Andrew Legan, a U of A postdoctoral fellow and first author of the study. Legan added that they found resistance was associated with a cluster of genes that was duplicated in some resistant field populations. However, it remains a mystery as to how many of these genes contribute to resistance and how they confer resistance.

 

Despite not narrowing the cause of resistance to a single gene, researchers say their study provides an important reminder that the genetic basis of resistance can differ between the field and lab.

 

For more details, read the article in U of A News.

 

See https://www.isaaa.org/kc/cropbiotechupdate/article/default.asp?ID=21070

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