Welcome To Website IAS

Hot news

Independence Award

- First Rank - Second Rank - Third Rank

Labour Award

- First Rank - Second Rank -Third Rank

National Award

 - Study on food stuff for animal(2005)

 - Study on rice breeding for export and domestic consumption(2005)


- Hybrid Maize by Single Cross V2002 (2003)

- Tomato Grafting to Manage Ralstonia Disease(2005)

- Cassava variety KM140(2010)

Website links
Vietnamese calendar
Visitors summary
 Curently online :  4
 Total visitors :  5629018

Study Shows Link between CRISPR and Mutated Cancer Cells
Saturday, 2021/12/04 | 04:14:23

Experts from Karolinska Institutet in Sweden reported a connection between CRISPR, a protein that protects cells from DNA damage known as p53, and other cancer genes. The results, published in Cancer Research, contribute more information to precision medicine.


CRISPR has been a popular gene editing tool in research. However, some hurdles need to be addressed to be used efficiently in precision medicine. One of these challenges is associated with how cells respond to DNA damage, which CRISPR gene editing causes in a controlled fashion. Cell damage activates p53, which is the cell's first aid response to DNA damage. When p53 is active while CRISPR is applied, the technique becomes less effective, while the absence of p53 can cause cells to grow beyond control and become cancerous.


The researchers reported that cells with inactivating mutations of the p45 gene have better survival when CRISPR is applied and thus can accumulate in a mixed cell population. They also found a network of related genes with mutations that have a similar impact to p53 mutations. The temporary inhibition of p53 was concluded to be a potential strategy for the enrichment of cells with such mutations.


Read more findings in Cancer Research and Science Daily.

Back      Print      View: 32

[ Other News ]___________________________________________________
  • Egypt Holds Workshop on New Biotech Applications
  • UN Agencies Urge Transformation of Food Systems
  • Taiwan strongly supports management of brown planthopper—a major threat to rice production
  • IRRI Director General enjoins ASEAN states to invest in science for global food security
  • Rabies: Educate, vaccinate and eliminate
  • “As a wife I will help, manage, and love”: The value of qualitative research in understanding land tenure and gender in Ghana
  • CIP Director General Wells Reflects on CIP’s 45th Anniversary
  • Setting the record straight on oil palm and peat in SE Asia
  • Why insect pests love monocultures, and how plant diversity could change that
  • Researchers Modify Yeast to Show How Plants Respond to Auxin
  • GM Maize MIR162 Harvested in Large Scale Field Trial in Vinh Phuc, Vietnam
  • Conference Tackles Legal Obligations and Compensation on Biosafety Regulations in Vietnam
  • Iloilo Stakeholders Informed about New Biosafety Regulations in PH
  • Global wheat and rice harvests poised to set new record
  • GM Maize Harvested in Vietnam Field Trial Sites
  • New label for mountain products puts premium on biological and cultural diversity
  • The Nobel Prize in Physiology or Medicine 2016
  • Shalabh Dixit: The link between rice genes and rice farmers
  • People need affordable food, but prices must provide decent livelihoods for small-scale family farmers
  • GM Seeds Market Growth to Increase through 2020 Due to Rise in Biofuels Use


Designed & Powered by WEBSO CO.,LTD