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BTI Scientists Develop New Technique to Boost Beta-carotene in Tubers

Scientists from Boyce Thompson Institute (BTI) and Donald Danforth Plant Science Center are working towards developing vitamin A-enriched tubers. Assistant Professor Joyce Van Eck of BTI developed a new technique for building up beta-carotene, the precursor of vitamin A, in potatoes. With the help of experts from Danforth, this technique will be used to develop biofortified cassava roots.

Scientists from Boyce Thompson Institute (BTI) and Donald Danforth Plant Science Center are working towards developing vitamin A-enriched tubers. Assistant Professor Joyce Van Eck of BTI developed a new technique for building up beta-carotene, the precursor of vitamin A, in potatoes. With the help of experts from Danforth, this technique will be used to develop biofortified cassava roots.

 

The new technique includes inserting of a specially designed DNA segment into the genome of potato to turn off the gene that codes for the enzyme that converts beta-carotene into zeaxanthin, a carotenoid like beta-carotene but cannot be converted into vitamin A. This then leads to accumulation of beta-carotene, in such amount that is enough to satisfy up to 18 percent of a toddler's required daily intake of vitamin A. The team is planning to add more strategies to further increase the levels of beta-carotene. 

 

Van Eck is now working with the Danforth team to transfer the technology to cassava plants. If successful, the vitamin A-enriched cassava will help decrease the number of children with vitamin A deficiency (VAD), particularly in Africa and South Asia where VAD is prevalent. 

 

Read more about the study from BTI.

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