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New crispr database to catalyze collaborations

To keep track of the increasingly large amounts of data from studies conducted using new gene editingtools, researchers at the at the Boyce Thompson Institute (BTI) developed the Plant Genome Editing Database (PGED) to be a central repository for efficiently managing plant mutant data, as well as to provide a platform for sharing the data and mutants with the research community.

To keep track of the increasingly large amounts of data from studies conducted using new gene editingtools, researchers at the at the Boyce Thompson Institute (BTI) developed the Plant Genome Editing Database (PGED) to be a central repository for efficiently managing plant mutant data, as well as to provide a platform for sharing the data and mutants with the research community. 

 

PGED will help lead to more efficient use of resources by reducing unnecessary duplicate experiments and catalyzing collaborations among research institutions. To help spread the word about the database's creation, the researchers recently published a call for data submission to PGED in the journal Molecular Plant.

 

The database currently contains data generated by BTI's Greg Martin lab on 432 tomato lines created with CRISPR-Cas editing. Martin notes that while CRISPR-Cas-generated lines are the main focus of PGED, it can also be used for plant mutants generated by other genome editing tools like meganucleases, zinc finger nucleases (ZFNs), and transcription activator-like nucleases (TALENs).

 

Read more about PGED in the BTI news release.

Figure: Postdoctoral scientist Ning Zhang inspects CRISPR/Cas-edited tomatoes in a greenhouse at BTI.

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